Marginal notes on North American Indians in Champlain's "Voyages de la Nouvelle France..." Includes one page of remarks on Canadian Indians, and a one-page list of words of Montagnais language.

In October 1719, the Yearly Meeting of the Society of Friends for Philadelphia and the Jersies reached consensus on a "book of discipline" governing the "establishment and order of meetings." The regulations covered both the conduct of the Quarterly and Monthly Meetings and the personal comportment of individual members, refining the bureaucratic structure of the meetings and laying out the powers of Overseers and other officials. It touches upon marriage (mandating endogamy), burial, and attendance at meetings, and cautions Friends to plainness of speech and dress, drinking, smoking, backbiting, and gaming. This version of the Book of Discipline is a manuscript copy made for the American Philosophical Society in 1820 "from and antient Copy in the possession of Timothy Matlack, Esqr."

These documents are principally of Pennsylvania interest, 1757-1809, including letters to Richard I. Manning from John C. Calhoun, Marquis de Lafayette, George McDuffie, and William Wirt. There are also letters of Clement C. Biddle, James Buchanan, Francis J. Grund, James Madison, Timothy Pickering, and William H. Seward. In addition, there are several musical scores (n.d.) and 19 cancelled checks (1861-1871) drawn by Ticknor and Fields in Boston, to the order of various American authors.

Founded in 1743 by Benjamin Franklin, the American Philosophical Society was the first learned society in the United States. For over 250 years, the Society has played an important role in American cultural and intellectual life. Until the mid-nineteenth century, the Society fulfilled the role of a national academy of science, national library and museum, and even patent office. Early members of the Society included Thomas Jefferson, David Rittenhouse, Benjamin Rush, Stephen Peter Du Ponceau, George Washington, and many other figures prominent in American history. The Archives of the American Philosophical Society consists of 192.25 linear feet of material, organized into thirteen record groups dating back to 1743. The Society's archives extensively documents not only the organization's historical development but also its role in American history and the history of science and technology.

James Burd (1726-1793) was well-known in colonial Pennsylvania through his role in the French and Indian War, as well as his connections to many of the colony's leading families (most notably the Shippen family). Initially starting out as a merchant in Philadelphia, Burd became increasingly involved with colonial affairs after moving to Lancaster County with his family in 1752. It would be on the frontier where Burd would make his mark first as a soldier, and later as a magistrate. The Burd-Shippen Papers consist mainly of letters and business documents sent to James Burd, with the bulk of the collection relating to the French and Indian War, 1754-1763, in which Burd served as an officer commanding troops at Fort Augusta and elsewhere. The collection reflects all aspects of Burd's life in Pennsylvania as a merchant, soldier, and magistrate; as well as his involvement with the Shippen family professionally and personally. Intermixed with items sent to Burd are receipts to his wife Sarah Shippen Burd, and correspondence between Edward Shippen and James Hamilton regarding land matters and Indian affairs in Lancaster.

A product of the distinctive culture of reform in antebellum Philadelphia, William Parker Foulke was the scion of the old elite who put a conservative stamp on social change. Trained as an attorney, Foulke spent much of his adult life engaging his deep amateur interest in natural history and mental philosophy and devoting himself to a variety of civic and philanthropic causes, including the colonization of formerly enslaved persons, penal reform, and cultural institutions in his native Philadelphia. The Foulke Papers are the product of the diverse social and intellectual interests of the Philadelphia attorney and philanthropist William Parker Foulke. Consisting primarily of correspondence, notes, and essays, the collection touches on Foulke's many interests. The collection includes numerous lectures delivered by Foulke along with material on the Lancaster County Prison, New York Prison Association, and the Philadelphia Society For Alleviating the Miseries of Public Prisons; notebooks concerning prisons and prisoners, including a 1846-1852 diary, and a listing of prisoners, their race, age, crime, sentence, and observations; a diary concerning the American Colonization Society (1852); a copy of an arctic diary (1853-1854) by John Wall Wilson, in the hand of Isaac Israel Hayes, which recounts much of the journey aboard the brig Advance, commanded by Elisha Kent Kane. There is also a list of buildings (1820-1841) designed by John Haviland, and material on the American Academy of Music, Philadelphia.